The Inhibitory Effect of Kakkonto, Japanese Traditional (Kampo) Medicine, on Brain Penetration of Oseltamivir Carboxylate in Mice with Reduced Blood-Brain Barrier Function

Oseltamivir phosphate (OP) is used to treat influenza virus infections. However, its use may result in central nervous system (CNS) adverse effects. In Japan, OP is used with Kampo formulations to improve clinical effectiveness. We evaluated the potential for using Kampo formulations to reduce CNS a...

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Bibliografische gegevens
Gepubliceerd in:Evid Based Complement Alternat Med
Hoofdauteurs: Ohara, Kousuke, Oshima, Shinji, Fukuda, Nanami, Ochiai, Yumiko, Maruyama, Ayumi, Kanamuro, Aki, Negishi, Akio, Honma, Seiichi, Ohshima, Shigeru, Akimoto, Masayuki, Takenaka, Shingo, Kobayashi, Daisuke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350872/
https://ncbi.nlm.nih.gov/pubmed/25788966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/917670
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