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Induction of Excessive Endoplasmic Reticulum Stress in the Drosophila Male Accessory Gland Results in Infertility

Endoplasmic reticulum (ER) stress occurs when misfolded proteins accumulate in the lumen of the ER. A cell responds to ER stress with the unfolded protein response (UPR), a complex program of transcriptional and translational changes aimed at clearing misfolded proteins. Secretory tissues and cells...

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Veröffentlicht in:PLoS One
Hauptverfasser: Chow, Clement Y., Avila, Frank W., Clark, Andrew G., Wolfner, Mariana F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350844/
https://ncbi.nlm.nih.gov/pubmed/25742606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119386
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