Is It Important to Adapt Neoadjuvant Chemotherapy to the Visible Clinical Response? An Open Randomized Phase II Study Comparing Response-Guided and Standard Treatments in HER2-Negative Operable Breast Cancer

BACKGROUND. Neoadjuvant treatment provides a unique opportunity to evaluate individual tumor sensitivity. This study evaluated whether a response-guided strategy could improve clinical outcome compared with a standard treatment. METHODS. Overall, 264 previously untreated stage II–III operable breast...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Wang-Lopez, Qian, Mouret-Reynier, Marie-Ange, Savoye, Aude-Marie, Abrial, Catherine, Kwiatkowski, Fabrice, Garbar, Christian, DuBray-Longeras, Pascale, Eymard, Jean-Christophe, Lebouedec, Guillaume, Vanpraagh, Isabelle, Penault-Llorca, Frederique, Chollet, Philippe, Cure, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2015
Assuntos:
Clinical Trial Results
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350805/
https://ncbi.nlm.nih.gov/pubmed/25637380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0400
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