Crystal structure of (S)-2-[(3S,8S,9S,10R,13S,14S,17R)-3-hy­droxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetra­deca­hydro-1H-cyclo­penta[a]phenanthren-17-yl]-N-meth­oxy-N-methyl­pro­pan­amide (Fernholz Weinreb amide)

The literature compound 3β-hy­droxy-bis­nor-5-cholenic aldehyde is an important inter­mediate for the synthesis of new modulators of the nuclear oxysterol receptor Liver X. As part of our ongoing search for new LXR antagonists, the title compound, C(24)H(39)NO(3), has proven to be an important inter...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Acta Crystallogr E Crystallogr Commun
Hlavní autoři: Viktorsson, Elvar Ørn, Åstrand, Ove Alexander Høgmoen, Haseeb, Rasha Sabah, Görbitz, Carl Henrik, Rongved, Pål
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2015
Témata:
Research Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350737/
https://ncbi.nlm.nih.gov/pubmed/25844186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2056989015001747
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky