Crystal structure of (S)-2-[(3S,8S,9S,10R,13S,14S,17R)-3-hy­droxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetra­deca­hydro-1H-cyclo­penta[a]phenanthren-17-yl]-N-meth­oxy-N-methyl­pro­pan­amide (Fernholz Weinreb amide)

The literature compound 3β-hy­droxy-bis­nor-5-cholenic aldehyde is an important inter­mediate for the synthesis of new modulators of the nuclear oxysterol receptor Liver X. As part of our ongoing search for new LXR antagonists, the title compound, C(24)H(39)NO(3), has proven to be an important inter...

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Detalles Bibliográficos
Publicado en:Acta Crystallogr E Crystallogr Commun
Main Authors: Viktorsson, Elvar Ørn, Åstrand, Ove Alexander Høgmoen, Haseeb, Rasha Sabah, Görbitz, Carl Henrik, Rongved, Pål
Formato: Artigo
Idioma:Inglês
Publicado: International Union of Crystallography 2015
Assuntos:
Research Communications
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350737/
https://ncbi.nlm.nih.gov/pubmed/25844186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2056989015001747
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