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Crystal structure of N-{N-[N-acetyl-(S)-leucyl]-(S)-leucyl}norleucinal (ALLN), an inhibitor of proteasome
The title compound, C(20)H(37)N(3)O(4), also known by the acronym ALLN, is a tripeptidic inhibitor of the proteolytic activity of the proteasomes, enzyme complexes implicated in several neurodegenerative diseases and other disorders, including cancer. The crystal structure of ALLN, solved from synch...
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Publicado no: | Acta Crystallogr E Crystallogr Commun |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
International Union of Crystallography
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4350719/ https://ncbi.nlm.nih.gov/pubmed/25844180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2056989015002091 |
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