The Mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Mitochondria are known to be functional organelles, but their role as a signaling unit is increasingly being appreciated. The identification of a short open reading frame (sORF) in the mitochondrial DNA (mtDNA) that encodes a signaling peptide, humanin, suggests the possible existence of additional...

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Bibliographic Details
Published in:Cell Metab
Main Authors: Lee, Changhan, Zeng, Jennifer, Drew, Brian G., Sallam, Tamer, Martin-Montalvo, Alejandro, Wan, Junxiang, Kim, Su-Jeong, Mehta, Hemal, Hevener, Andrea L., de Cabo, Rafael, Cohen, Pinchas
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350682/
https://ncbi.nlm.nih.gov/pubmed/25738459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.02.009
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