Identification of a family of fatty acid-speciated Sonic Hedgehog proteins, whose members display differential biological properties

Hedgehog (HH) proteins are proteolytically processed into a biologically active form, which is covalently modified by cholesterol and palmitate. However, most studies of HH biogenesis have characterized protein from cells in which HH is over-expressed. We purified Sonic Hedgehog (SHH) from cells exp...

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Publicat a:Cell Rep
Autors principals: Long, Jun, Tokhunts, Robert, Old, William M., Houel, Stephane, Rodgriguez-Blanco, Jezabel, Singh, Samer, Schilling, Neal, J.Capobianco, Anthony, Ahn, Natalie G., Robbins, David J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350664/
https://ncbi.nlm.nih.gov/pubmed/25732819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.01.058
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