Involvement of metformin and AMPK in the radioresponse and prognosis of luminal versus basal-like breast cancer treated with radiotherapy

Metformin is under evaluation as a potential anticancer agent. Expression of total and phospho(Thr172)-adenosine monophosphate-activated kinase-α (AMPKα and pAMPKα(Thr172) respectively), a main metformin target, was examined in radiotherapy treated breast cancers and metformin's ability to modu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Yimin, Storr, Sarah J., Johnson, Kerstie, Green, Andrew R., Rakha, Emad A., Ellis, Ian O., Morgan, David A.L., Martin, Stewart G.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350336/
https://ncbi.nlm.nih.gov/pubmed/25427448
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