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PCH-2 regulates Caenorhabditis elegans lifespan

Components or downstream targets of many signaling pathways such as Insulin/IGF-1 and TOR, as well as genes involved in cellular metabolism and bioenergetics can extend worm lifespan 20% or more. The C. elegans gene pch-2 and its homologs, including TRIP13 in humans, have been studied for their func...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Qian, Hong, Xu, Xiangru, Niklason, Laura E
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350321/
https://ncbi.nlm.nih.gov/pubmed/25635513
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