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Precise in-frame integration of exogenous DNA mediated by CRISPR/Cas9 system in zebrafish
The CRISPR/Cas9 system provides a powerful tool for genome editing in various model organisms, including zebrafish. The establishment of targeted gene-disrupted zebrafish (knockouts) is readily achieved by CRISPR/Cas9-mediated genome modification. Recently, exogenous DNA integration into the zebrafi...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4350073/ https://ncbi.nlm.nih.gov/pubmed/25740433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08841 |
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