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Reverse-Polynomial Dilution Calibration Methodology Extends Lower Limit of Quantification and Reduces Relative Residual Error in Targeted Peptide Measurements in Blood Plasma

Matrix effect is the alteration of an analyte's concentration-signal response caused by co-existing ion components. With electrospray ionization (ESI), matrix effects are believed to be a function of the relative concentrations, ionization efficiency, and solvation energies of the analytes with...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Yau, Yunki Y., Duo, Xizi, Leong, Rupert W.L., Wasinger, Valerie C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350038/
https://ncbi.nlm.nih.gov/pubmed/25492093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.040790
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