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Post-translational Modifications Regulate Class IIa Histone Deacetylase (HDAC) Function in Health and Disease

Class IIa histone deacetylases (HDACs4, -5, -7, and -9) modulate the physiology of the human cardiovascular, musculoskeletal, nervous, and immune systems. The regulatory capacity of this family of enzymes stems from their ability to shuttle between nuclear and cytoplasmic compartments in response to...

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Pubblicato in:Mol Cell Proteomics
Autori principali: Mathias, Rommel A., Guise, Amanda J., Cristea, Ileana M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349969/
https://ncbi.nlm.nih.gov/pubmed/25616866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O114.046565
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