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GSK-3β suppresses the proliferation of rat hepatic oval cells through modulating Wnt/β-catenin signaling pathway

AIM: Glycogen synthase kinase 3β (GSK-3β) plays a crucial role in hepatic biology, including liver development, regeneration, proliferation and carcinogenesis. In this study we investigated the role of GSK-3β in regulation of growth of hepatic oval cells in vitro and in liver regeneration in partial...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Ji, Xiao-ke, Xie, Yuan-kang, Zhong, Jun-qiao, Xu, Qi-gang, Zeng, Qi-qiang, Wang, Yang, Zhang, Qi-yu, Shan, Yun-feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349928/
https://ncbi.nlm.nih.gov/pubmed/25661318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.150
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