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Identifying Prognostic Features by Bottom-Up Approach and Correlating to Drug Repositioning

BACKGROUND: Traditionally top-down method was used to identify prognostic features in cancer research. That is to say, differentially expressed genes usually in cancer versus normal were identified to see if they possess survival prediction power. The problem is that prognostic features identified f...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Li, Wei, Yu, Jian, Lian, Baofeng, Sun, Han, Li, Jing, Zhang, Menghuan, Li, Ling, Li, Yixue, Liu, Qian, Xie, Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349868/
https://ncbi.nlm.nih.gov/pubmed/25738841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118672
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