Innovative Delivery of siRNA to Solid Tumors by Super Carbonate Apatite

RNA interference (RNAi) technology is currently being tested in clinical trials for a limited number of diseases. However, systemic delivery of small interfering RNA (siRNA) to solid tumors has not yet been achieved in clinics. Here, we introduce an in vivo pH-sensitive delivery system for siRNA usi...

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Publicado en:PLoS One
Autores principales: Wu, Xin, Yamamoto, Hirofumi, Nakanishi, Hiroyuki, Yamamoto, Yuki, Inoue, Akira, Tei, Mitsuyoshi, Hirose, Hajime, Uemura, Mamoru, Nishimura, Junichi, Hata, Taishi, Takemasa, Ichiro, Mizushima, Tsunekazu, Hossain, Sharif, Akaike, Toshihiro, Matsuura, Nariaki, Doki, Yuichiro, Mori, Masaki
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349808/
https://ncbi.nlm.nih.gov/pubmed/25738937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116022
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