Mammary gland tumor promotion by chronic administration of IGF1 and the insulin analogue AspB10 in the p53(R270H/+)WAPCre mouse model

INTRODUCTION: Insulin analogues are structurally modified molecules with altered pharmaco-kinetic and -dynamic properties compared to regular human insulin used by diabetic patients. While these compounds are tested for undesired mitogenic effects, an epidemiological discussion is ongoing regarding...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: ter Braak, Bas, Siezen, Christine, Speksnijder, Ewoud N, Koedoot, Esmee, van Steeg, Harry, Salvatori, Daniela CF, van de Water, Bob, van der Laan, Jan Willem
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349771/
https://ncbi.nlm.nih.gov/pubmed/25848982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-015-0518-y
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