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Man is not a big rat: concerns with traditional human risk assessment of phthalates based on their anti-androgenic effects observed in the rat foetus

Phthalates provide one of the most documented example evidencing how much we must be cautious when using the traditional paradigm based on extrapolation of experimental data from rodent studies for human health risk assessment of endocrine disruptors (EDs). Since foetal testis is known as one of the...

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Bibliographic Details
Published in:Basic Clin Androl
Main Authors: Habert, René, Livera, Gabriel, Rouiller-Fabre, Virginie
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349750/
https://ncbi.nlm.nih.gov/pubmed/25780587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-4190-24-14
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