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Modified Vaccinia virus Ankara but not vaccinia virus induces chemokine expression in cells of the monocyte/macrophage lineage

BACKGROUND: The orthopoxvirus strain Modified Vaccinia virus Ankara (MVA) rapidly induces innate immune responses. Previously, we demonstrated that CCL2 and CCR1 are important players in MVA induced recruitment of leukocytes to the lung. Alveolar macrophages are sentinel cells in the lung, which are...

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Pubblicato in:Virol J
Autori principali: Lehmann, Michael H, Price, Philip JR, Brandmüller, Christine, Sutter, Gerd
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349667/
https://ncbi.nlm.nih.gov/pubmed/25889495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0252-1
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