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A Rapid Molecular Approach for Chromosomal Phasing

Determining the chromosomal phase of pairs of sequence variants – the arrangement of specific alleles as haplotypes – is a routine challenge in molecular genetics. Here we describe Drop-Phase, a molecular method for quickly ascertaining the phase of pairs of DNA sequence variants (separated by 1-200...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Regan, John F., Kamitaki, Nolan, Legler, Tina, Cooper, Samantha, Klitgord, Niels, Karlin-Neumann, George, Wong, Catherine, Hodges, Shawn, Koehler, Ryan, Tzonev, Svilen, McCarroll, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349636/
https://ncbi.nlm.nih.gov/pubmed/25739099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118270
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