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Limitations of the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay when compared to three commonly used cell enumeration assays

BACKGROUND: The tetrazolium-based MTT assay has long been regarded as the gold standard of cytotoxicity assays as it is highly sensitive and has been miniaturised for use as a high-throughput screening assay. However, various reports refer to interference by different test compounds, including the g...

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Détails bibliographiques
Publié dans:BMC Res Notes
Auteurs principaux: van Tonder, Alet, Joubert, Annie M, Cromarty, A Duncan
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349615/
https://ncbi.nlm.nih.gov/pubmed/25884200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-015-1000-8
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