Opposing Effects of Low Molecular Weight Heparins on the Release of Inflammatory Cytokines from Peripheral Blood Mononuclear Cells of Asthmatics

BACKGROUND: T-cell-mediated inflammatory cytokines, such as interleukin (IL)-4, IL-5, IL-13 and tumor necrosis factor-alpha (TNF-α), play an important role in the initiation and progression of inflammatory airways diseases. Low-molecular-weight heparins (LMWHs), widely used anticoagulants, possess a...

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Bibliographic Details
Published in:PLoS One
Main Authors: Shastri, Madhur D., Stewart, Niall, Eapen, Mathew, Peterson, Gregory M., Zaidi, Syed Tabish R., Gueven, Nuri, Sohal, Sukhwinder Singh, Patel, Rahul P.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349593/
https://ncbi.nlm.nih.gov/pubmed/25738575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118798
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