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Structural Insights into Assembly and Regulation of the Plasma Membrane Phosphatidylinositol 4-Kinase Complex

Plasma membrane PI4P helps determine the identity of this membrane and plays a key role in signal transduction as the precursor of PI(4,5)P(2) and its metabolites. Here, we report the atomic structure of the protein scaffold that is required for the plasma membrane localization and function of Stt4/...

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Bibliographic Details
Published in:Dev Cell
Main Authors: Wu, Xudong, Chi, Richard J., Baskin, Jeremy M., Lucast, Louise, Burd, Christopher G., De Camilli, Pietro, Reinisch, Karin M.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349574/
https://ncbi.nlm.nih.gov/pubmed/24360784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.11.012
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