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Specific disruption of thalamic inputs to the auditory cortex in schizophrenia models

Auditory hallucinations in schizophrenia are alleviated by antipsychotic agents that inhibit D2 dopamine receptors (Drd2s). The defective neural circuits and mechanisms of their sensitivity to antipsychotics are unknown. We identified a specific disruption of synaptic transmission at thalamocortical...

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Pubblicato in:Science
Autori principali: Chun, Sungkun, Westmoreland, Joby J., Bayazitov, Ildar T., Eddins, Donnie, Pani, Amar K., Smeyne, Richard J., Yu, Jing, Blundon, Jay A., Zakharenko, Stanislav S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349506/
https://ncbi.nlm.nih.gov/pubmed/24904170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1253895
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