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Licensing of Primordial Germ Cells for Gametogenesis Depends on Genital Ridge Signaling
In mouse embryos at mid-gestation, primordial germ cells (PGCs) undergo licensing to become gametogenesis-competent cells (GCCs), gaining the capacity for meiotic initiation and sexual differentiation. GCCs then initiate either oogenesis or spermatogenesis in response to gonadal cues. Germ cell lice...
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| Publicado no: | PLoS Genet |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4349450/ https://ncbi.nlm.nih.gov/pubmed/25739037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005019 |
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