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Synthesis and Evaluation of Mefway Analogs as Ligands for Serotonin 5HT(1A) Receptors

(18)F-Mefway (N-{2-[4-(2′-methoxyphenyl)piperazinyl]ethyl}-N-(2-pyridyl)-N-(4′-(18)F-fluoro-methylcyclohexane)carboxamide) was developed and evaluated for use as a PET ligand for imaging 5-HT(1A) receptors. Ongoing studies of (18)F-Mefway have shown it to be an effective PET radiotracer. We have syn...

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Publicat a:Med Chem Res
Autors principals: Thio, Joanne P., Liang, Christopher, Bajwa, Alisha K., Wooten, Dustin W., Christian, Bradley T., Mukherjee, Jogeshwar
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349336/
https://ncbi.nlm.nih.gov/pubmed/25750500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-014-1238-z
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