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Postmitotic Nuclear Retention of Episomal Plasmids Is Altered by DNA Labeling and Detection Methods

One often overlooked aspect of nonviral gene therapy is the maintenance and localization of plasmids within a transfected cell. In this study we have quantified the nuclear retention of plasmids within microinjected cells after a single round of cell division. We employed several commercially availa...

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Podrobná bibliografie
Vydáno v:Mol Ther
Hlavní autoři: Gasiorowski, Joshua Z., Dean, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349329/
https://ncbi.nlm.nih.gov/pubmed/15978873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2005.05.001
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