Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting

Next-generation sequencing has revealed novel recurrent mutations in chronic lymphocytic leukemia, particularly in patients with aggressive disease. Here, we explored targeted re-sequencing as a novel strategy to assess the mutation status of genes with prognostic potential. To this end, we utilized...

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Veröffentlicht in:Haematologica
Hauptverfasser: Sutton, Lesley-Ann, Ljungström, Viktor, Mansouri, Larry, Young, Emma, Cortese, Diego, Navrkalova, Veronika, Malcikova, Jitka, Muggen, Alice F., Trbusek, Martin, Panagiotidis, Panagiotis, Davi, Frederic, Belessi, Chrysoula, Langerak, Anton W., Ghia, Paolo, Pospisilova, Sarka, Stamatopoulos, Kostas, Rosenquist, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2015
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349276/
https://ncbi.nlm.nih.gov/pubmed/25480502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.109777
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