Revisiting the immune microenvironment of diffuse large B-cell lymphoma using a tissue microarray and immunohistochemistry: robust semi-automated analysis reveals CD3 and FoxP3 as potential predictors of response to R-CHOP

Gene expression studies have identified the microenvironment as a prognostic player in diffuse large B-cell lymphoma. However, there is a lack of simple immune biomarkers that can be applied in the clinical setting and could be helpful in stratifying patients. Immunohistochemistry has been used for...

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Publié dans:Haematologica
Auteurs principaux: Coutinho, Rita, Clear, Andrew J., Mazzola, Emanuele, Owen, Andrew, Greaves, Paul, Wilson, Andrew, Matthews, Janet, Lee, Abigail, Alvarez, Rute, da Silva, Maria Gomes, Cabeçadas, José, Neuberg, Donna, Calaminici, Maria, Gribben, John G.
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2015
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349275/
https://ncbi.nlm.nih.gov/pubmed/25425693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.110189
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