PD-1 expression defines two distinct T-cell sub-populations in follicular lymphoma that differentially impact patient survival

To determine the biological and clinical relevance of programmed death 1 (PD-1) in follicular lymphoma (FL), we characterized PD-1(+) T-cell subsets and assessed their biological function as well as potential clinical impact. We found that PD-1 is expressed on intratumoral CD4(+) T cells with both b...

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Veröffentlicht in:Blood Cancer J
Hauptverfasser: Yang, Z -Z, Grote, D M, Ziesmer, S C, Xiu, B, Novak, A J, Ansell, S M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349259/
https://ncbi.nlm.nih.gov/pubmed/25700246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2015.1
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