Recurrent gain-of-function USP8 mutations in Cushing's disease

Cushing's disease, also known as adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas (PAs) that cause excess cortisol production, accounts for up to 85% of corticotrophin-dependent Cushing's syndrome cases. However, the genetic alterations in this disease are unclear. Here, we...

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Published in:Cell Res
Main Authors: Ma, Zeng-Yi, Song, Zhi-Jian, Chen, Jian-Hua, Wang, Yong-Fei, Li, Shi-Qi, Zhou, Liang-Fu, Mao, Ying, Li, Yi-Ming, Hu, Rong-Gui, Zhang, Zhao-Yun, Ye, Hong-Ying, Shen, Ming, Shou, Xue-Fei, Li, Zhi-Qiang, Peng, Hong, Wang, Qing-Zhong, Zhou, Dai-Zhan, Qin, Xiao-Lan, Ji, Jue, Zheng, Jie, Chen, Hong, Wang, Yin, Geng, Dao-Ying, Tang, Wei-Jun, Fu, Chao-Wei, Shi, Zhi-Feng, Zhang, Yi-Chao, Ye, Zhao, He, Wen-Qiang, Zhang, Qi-Lin, Tang, Qi-Sheng, Xie, Rong, Shen, Jia-Wei, Wen, Zu-Jia, Zhou, Juan, Wang, Tao, Huang, Shan, Qiu, Hui-Jia, Qiao, Ni-Dan, Zhang, Yi, Pan, Li, Bao, Wei-Min, Liu, Ying-Chao, Huang, Chuan-Xin, Shi, Yong-Yong, Zhao, Yao
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349249/
https://ncbi.nlm.nih.gov/pubmed/25675982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.20
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