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Hydrolytic Fitness of N-glycosyl Bonds: Comparing the Deglycosylation Kinetics of Modified, Alternative and Native Nucleosides

Nature’s selection of the contemporary nucleobases in RNA and DNA continues to intrigue the origin of life community. While the prebiotic synthesis of the N-glycosyl bond has historically been a central area of investigation, variations in hydrolytic stabilities among the N-glycosyl bonds may have p...

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Bibliografiske detaljer
Udgivet i:J Phys Org Chem
Main Authors: Rios, Andro C, Yu, Hiu T, Tor, Yitzhak
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349208/
https://ncbi.nlm.nih.gov/pubmed/25750482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/poc.3318
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