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Quality Control of Genotypes Using Heritability Estimates of Gene Content at the Marker

Quality control filtering of single-nucleotide polymorphisms (SNPs) is a key step when analyzing genomic data. Here we present a practical method to identify low-quality SNPs, meaning markers whose genotypes are wrongly assigned for a large proportion of individuals, by estimating the heritability o...

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Bibliografski detalji
Izdano u:Genetics
Glavni autori: Forneris, Natalia S., Legarra, Andres, Vitezica, Zulma G., Tsuruta, Shogo, Aguilar, Ignacio, Misztal, Ignacy, Cantet, Rodolfo J. C.
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349063/
https://ncbi.nlm.nih.gov/pubmed/25567991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.173559
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