Oxido-reductive regulation of vascular remodeling by receptor tyrosine kinase ROS1

Angioplasty and stenting is the primary treatment for flow-limiting atherosclerosis; however, this strategy is limited by pathological vascular remodeling. Using a systems approach, we identified a role for the network hub gene glutathione peroxidase-1 (GPX1) in pathological remodeling following hum...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Ali, Ziad A., de Jesus Perez, Vinicio, Yuan, Ke, Orcholski, Mark, Pan, Stephen, Qi, Wei, Chopra, Gaurav, Adams, Christopher, Kojima, Yoko, Leeper, Nicholas J., Qu, Xiumei, Zaleta-Rivera, Kathia, Kato, Kimihiko, Yamada, Yoshiji, Oguri, Mitsutoshi, Kuchinsky, Allan, Hazen, Stanley L., Jukema, J. Wouter, Ganesh, Santhi K., Nabel, Elizabeth G., Channon, Keith, Leon, Martin B., Charest, Alain, Quertermous, Thomas, Ashley, Euan A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348976/
https://ncbi.nlm.nih.gov/pubmed/25401476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77484
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