RASAL2 activates RAC1 to promote triple-negative breast cancer progression

Patients with triple-negative breast cancer (TNBC) have a high incidence of early relapse and metastasis; however, the molecular basis for recurrence in these individuals remains poorly understood. Here, we demonstrate that RASAL2, which encodes a RAS-GTPase–activating protein (RAS-GAP), is a functi...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Feng, Min, Bao, Yi, Li, Zhimei, Li, Juntao, Gong, Min, Lam, Stella, Wang, Jinhua, Marzese, Diego M., Donovan, Nicholas, Tan, Ern Yu, Hoon, Dave S.B., Yu, Qiang
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348963/
https://ncbi.nlm.nih.gov/pubmed/25384218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76711
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