Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity

BACKGROUND: Inhalation of benzene at levels below the current exposure limit values leads to hematotoxicity in occupationally exposed workers. OBJECTIVE: We sought to evaluate Diversity Outbred (DO) mice as a tool for exposure threshold assessment and to identify genetic factors that influence benze...

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Detalhes bibliográficos
Publicado no:Environ Health Perspect
Main Authors: French, John E., Gatti, Daniel M., Morgan, Daniel L., Kissling, Grace E., Shockley, Keith R., Knudsen, Gabriel A., Shepard, Kim G., Price, Herman C., King, Deborah, Witt, Kristine L., Pedersen, Lars C., Munger, Steven C., Svenson, Karen L., Churchill, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: NLM-Export 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348743/
https://ncbi.nlm.nih.gov/pubmed/25376053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1408202
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