Src-Mediated EGF Receptor Activation Regulates Ozone-Induced Interleukin 8 Expression in Human Bronchial Epithelial Cells

BACKGROUND: Human exposure to ozone (O(3)) results in pulmonary function decrements and airway inflammation. The mechanisms underlying these adverse effects remain unclear. Epidermal growth factor receptor (EGFR) plays an important role in the pathogenesis of lung inflammation. OBJECTIVE: We examine...

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Dettagli Bibliografici
Pubblicato in:Environ Health Perspect
Autori principali: Wu, Weidong, Wages, Phillip A., Devlin, Robert B., Diaz-Sanchez, David, Peden, David B., Samet, James M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: NLM-Export 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348738/
https://ncbi.nlm.nih.gov/pubmed/25303742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1307379
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