SAFETY AND ACTIVITY OF TEMSIROLIMUS AND BEVACIZUMAB IN PATIENTS WITH ADVANCED RENAL CELL CARCINOMA PREVIOUSLY TREATED WITH TYROSINE KINASE INHIBITORS: A PHASE 2 CONSORTIUM STUDY

PURPOSE: Bevacizumab or Temsirolimus regimens have clinical activity in the first line treatment of advanced renal cell carcinoma (RCC). This phase I/II trial was conducted to determine the safety of combining both agents and its efficacy in RCC patients who progressed on at least one prior anti-VEG...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Merchan, Jaime R., Qin, Rui, Pitot, Henry, Picus, Joel, Liu, Glenn, Fitch, Tom, Maples, William J., Flynn, Patrick J., Fruth, Briant F., Erlichman, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348698/
https://ncbi.nlm.nih.gov/pubmed/25556030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2668-5
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