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MicroRNA-320a sensitizes tamoxifen-resistant breast cancer cells to tamoxifen by targeting ARPP-19 and ERRγ*

Tamoxifen represents a major adjuvant therapy to those patients with estrogen receptor-alpha positive breast cancer. However, tamoxifen resistance occurs quite often, either de novo or acquired during treatment. To investigate the role of miR-320a in the development of resistance to tamoxifen, we es...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lü, Mingrong, Ding, Keshuo, Zhang, Guofeng, Yin, Mianmian, Yao, Guidong, Tian, Hui, Lian, Jie, Liu, Lin, Liang, Meng, Zhu, Tao, Sun, Fei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348640/
https://ncbi.nlm.nih.gov/pubmed/25736597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08735
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