Exposure to the complement C5b-9 complex sensitizes 661W photoreceptor cells to both apoptosis and necroptosis

The loss of photoreceptors is the defining characteristic of many retinal degenerative diseases, but the mechanisms that regulate photoreceptor cell death are not fully understood. Here we have used the 661W cone photoreceptor cell line to ask whether exposure to the terminal complement complex C5b-...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Apoptosis
Prif Awduron: Shi, Hui, Williams, Jennifer A. E., Guo, Li, Stampoulis, Dimitrios, Francesca Cordeiro, M., Moss, Stephen E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer US 2015
Pynciau:
Original Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348505/
https://ncbi.nlm.nih.gov/pubmed/25735751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-015-1091-7
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