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L-carnitine enhances axonal plasticity and improves white-matter lesions after chronic hypoperfusion in rat brain

Chronic cerebral hypoperfusion causes white-matter lesions (WMLs) with oxidative stress and cognitive impairment. However, the biologic mechanisms that regulate axonal plasticity under chronic cerebral hypoperfusion have not been fully investigated. Here, we investigated whether L-carnitine, an anti...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Ueno, Yuji, Koike, Masato, Shimada, Yoshiaki, Shimura, Hideki, Hira, Kenichiro, Tanaka, Ryota, Uchiyama, Yasuo, Hattori, Nobutaka, Urabe, Takao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348379/
https://ncbi.nlm.nih.gov/pubmed/25465043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.210
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