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β1-Integrin Alters Ependymal Stem Cell BMP Receptor Localization and Attenuates Astrogliosis after Spinal Cord Injury

Astrogliosis after spinal cord injury (SCI) is a major impediment to functional recovery. More than half of new astrocytes generated after SCI are derived from ependymal zone stem cells (EZCs). We demonstrate that expression of β1-integrin increases in EZCs following SCI in mice. Conditional knock-o...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: North, Hilary A., Pan, Liuliu, McGuire, Tammy L., Brooker, Sarah, Kessler, John A.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348179/
https://ncbi.nlm.nih.gov/pubmed/25740503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4546-14.2015
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