Rph1/KDM4 mediates nutrient-limitation signaling that leads to the transcriptional induction of autophagy

BACKGROUND: Autophagy is a conserved process mediating vacuolar degradation and recycling. Autophagy is highly upregulated upon various stresses and is essential for cell survival in deleterious conditions. Autophagy defects are associated with severe pathologies, whereas unchecked autophagy activit...

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Udgivet i:Curr Biol
Main Authors: Bernard, Amélie, Jin, Meiyan, González-Rodríguez, Patricia, Füllgrabe, Jens, Delorme-Axford, Elizabeth, Backues, Steven K., Joseph, Bertrand, Klionsky, Daniel J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348152/
https://ncbi.nlm.nih.gov/pubmed/25660547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.12.049
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