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Functional effects of mutations in the tropomyosin-binding sites of tropomodulin1 and tropomodulin3

Tropomodulins (Tmods) interact with tropomyosins (TMs) via two TM-binding sites and cap the pointed ends of TM-coated actin filaments. To study the functional interplay between TM binding and TM-actin filament capping by Tmods, we introduced disabling mutations into the first, second, or both TM-bin...

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Dettagli Bibliografici
Pubblicato in:Cytoskeleton (Hoboken)
Autori principali: Lewis, Raymond A., Yamashiro, Sawako, Gokhin, David S., Fowler, Velia M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347929/
https://ncbi.nlm.nih.gov/pubmed/24922351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.21179
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