Exposure and genetics increase risk of beryllium sensitisation and chronic beryllium disease in the nuclear weapons industry

OBJECTIVES: Beryllium sensitisation (BeS) and chronic beryllium disease (CBD) are caused by exposure to beryllium with susceptibility affected by at least one well-studied genetic host factor, a glutamic acid residue at position 69 (E69) of the HLA-DPβ chain (DPβE69). However, the nature of the rela...

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Veröffentlicht in:Occup Environ Med
Hauptverfasser: Van Dyke, Michael V, Martyny, John W, Mroz, Margaret M, Silveira, Lori J, Strand, Matt, Cragle, Donna L, Tankersley, William G, Wells, Susan M, Newman, Lee S, Maier, Lisa A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347849/
https://ncbi.nlm.nih.gov/pubmed/21460389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/oem.2010.064220
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