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Substance P is essential for maintaining gut muscle contractility: a novel role for coneurotransmission revealed by botulinum toxin
Substance P (SP) is commonly coexpressed with ACh in enteric motor neurons, and, according to the classical paradigm, both these neurotransmitters excite smooth muscle via parallel pathways. We hypothesized that, in addition, SP was responsible for maintaining the muscular responsiveness to ACh. We...
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| Publicado no: | Am J Physiol Gastrointest Liver Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347745/ https://ncbi.nlm.nih.gov/pubmed/24699329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00436.2012 |
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