Role of Drosophila retinoblastoma protein instability element in cell growth and proliferation

The RB tumor suppressor, a regulator of the cell cycle, apoptosis, senescence, and differentiation, is frequently mutated in human cancers. We recently described an evolutionarily conserved C-terminal “instability element” (IE) of the Drosophila Rbf1 retinoblastoma protein that regulates its turnove...

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Bibliographic Details
Published in:Cell Cycle
Main Authors: Elenbaas, Jared S, Mouawad, Rima, Henry, R William, Arnosti, David N, Payankaulam, Sandhya
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347690/
https://ncbi.nlm.nih.gov/pubmed/25496208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.991182
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