TLR4 activation induces IL-1β release via an IPAF dependent but caspase 1/11/8 independent pathway in the lung

BACKGROUND: The IL-1 family of cytokines is known to play an important role in inflammation therefore understanding the mechanism by which they are produced is paramount. Despite the recent plethora of publications dedicated to the study of these cytokines, the mechanism by which they are produced i...

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Bibliographische Detailangaben
Veröffentlicht in:Respir Res
Hauptverfasser: Eltom, Suffwan, Belvisi, Maria G, Yew-Booth, Liang, Dekkak, Bilel, Maher, Sarah A, Dubuis, Eric D, Jones, Victoria, Fitzgerald, Kate A, Birrell, Mark A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347603/
https://ncbi.nlm.nih.gov/pubmed/25085021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-014-0087-0
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