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Synthetic signal sequences that enable efficient secretory protein production in the yeast Kluyveromyces marxianus

BACKGROUND: Targeting of cellular proteins to the extracellular environment is directed by a secretory signal sequence located at the N-terminus of a secretory protein. These signal sequences usually contain an N-terminal basic amino acid followed by a stretch containing hydrophobic residues, althou...

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Publicat a:Microb Cell Fact
Autors principals: Yarimizu, Tohru, Nakamura, Mikiko, Hoshida, Hisashi, Akada, Rinji
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347551/
https://ncbi.nlm.nih.gov/pubmed/25889890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0203-y
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