Fluoxetine induces alkalinization of astroglial cytosol through stimulation of sodium-hydrogen exchanger 1: dissection of intracellular signaling pathways

Clinical evidence suggest astrocytic abnormality in major depression (MD) while treatment with anti-psychotic drugs affects astroglial functions. Astroglial cells are involved in pH homeostasis of the brain by transporting protons (through sodium-proton transporter 1, NHE1, glutamate transporters EA...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Ren, Jienan, Song, Dan, Bai, Qiufang, Verkhratsky, Alexei, Peng, Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347488/
https://ncbi.nlm.nih.gov/pubmed/25784857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00061
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